Mixing 5-MeO-xxT and SSRIs

Mixing 5-MeO-xxT and SSRIs is relatively low-risk, though one may reduce the other’s effects — TripSit rates this combination “Low Risk & Decrease.” Low risk never means safe.

5-MeO-xxT and SSRIs (also known as most antidepressants).

What to do

• Even for lower-risk pairs, the safest choice is not to mix — and never to use alone.
• Start with much less than usual and go slow — you can always take more, never less.
• Never use alone. If you do, call 1-800-484-3731 (Never Use Alone) so someone can send help if you stop responding.

Open the interactive combination checker

Related combinations

• Mixing Opioids and 5-MeO-xxT
• Mixing Benzodiazepines and 5-MeO-xxT
• Mixing Alcohol and 5-MeO-xxT
• Mixing Cocaine and 5-MeO-xxT
• Mixing Amphetamines and 5-MeO-xxT
• Mixing MDMA and 5-MeO-xxT
• Mixing Cannabis and 5-MeO-xxT
• Mixing Ketamine and 5-MeO-xxT

This is educational information, not medical advice. "Low risk" never means "safe", and the potency of an unregulated supply is unknown.