Mixing Alcohol and MAOIs

Mixing Alcohol and MAOIs is unsafe and best avoided — TripSit rates this combination “Unsafe.” Low risk never means safe.

Tyramine found in many alcoholic beverages can have dangerous reactions with MAOIs, causing an increase in blood pressure.

Alcohol and MAOIs (also known as some antidepressants, syrian rue).

What to do

Avoid this combination — the safest choice is not to mix them.
Start with much less than usual and go slow — you can always take more, never less.
Never use alone. If you do, call 1-800-484-3731 (Never Use Alone) so someone can send help if you stop responding.

This is educational information, not medical advice. "Low risk" never means "safe", and the potency of an unregulated supply is unknown.