Mixing Cannabis and MAOIs

Mixing Cannabis and MAOIs is relatively low-risk, and effects may be stronger together — TripSit rates this combination “Low Risk & Synergy.” Low risk never means safe.

Cannabis (also known as weed, marijuana, THC) and MAOIs (also known as some antidepressants, syrian rue).

What to do

• Even for lower-risk pairs, the safest choice is not to mix — and never to use alone.
• Start with much less than usual and go slow — you can always take more, never less.
• Never use alone. If you do, call 1-800-484-3731 (Never Use Alone) so someone can send help if you stop responding.

Open the interactive combination checker

Related combinations

• Mixing Opioids and Cannabis
• Mixing Benzodiazepines and Cannabis
• Mixing Alcohol and Cannabis
• Mixing Cocaine and Cannabis
• Mixing Amphetamines and Cannabis
• Mixing MDMA and Cannabis
• Mixing Cannabis and Ketamine
• Mixing Cannabis and GHB / GBL

This is educational information, not medical advice. "Low risk" never means "safe", and the potency of an unregulated supply is unknown.