Mixing Cannabis and Pregabalin

Mixing Cannabis and Pregabalin is relatively low-risk, and effects may be stronger together — TripSit rates this combination “Low Risk & Synergy.” Low risk never means safe.

Both substances may increase each other's side effects, such as sedation, lowered blood pressure, and raised heart rate.

Cannabis (also known as weed, marijuana, THC) and Pregabalin (also known as Lyrica).

What to do

• Even for lower-risk pairs, the safest choice is not to mix — and never to use alone.
• Start with much less than usual and go slow — you can always take more, never less.
• Never use alone. If you do, call 1-800-484-3731 (Never Use Alone) so someone can send help if you stop responding.

Open the interactive combination checker

Related combinations

• Mixing Opioids and Cannabis
• Mixing Benzodiazepines and Cannabis
• Mixing Alcohol and Cannabis
• Mixing Cocaine and Cannabis
• Mixing Amphetamines and Cannabis
• Mixing MDMA and Cannabis
• Mixing Cannabis and Ketamine
• Mixing Cannabis and GHB / GBL

This is educational information, not medical advice. "Low risk" never means "safe", and the potency of an unregulated supply is unknown.