Mixing Cocaine and DPH

Mixing Cocaine and DPH calls for caution — TripSit rates this combination “Caution.” Low risk never means safe.

Stimulants increase respiration rate allowing for a higher dose of sedatives than normal. If cocaine wears off first, recreational dosages of DPH may overcome the individual and cause respiratory arrest. Both substances at recreational dosages strain the heart and may lead to further dangerous heart complications. When taken together, both substances can potentially be more reinforcing and have greater risk of methemoglobinemia when higher dosages of DPH are combined with cocaine.

Cocaine (also known as coke, crack) and DPH (also known as Benadryl).

What to do

• Even for lower-risk pairs, the safest choice is not to mix — and never to use alone.
• Start with much less than usual and go slow — you can always take more, never less.
• Never use alone. If you do, call 1-800-484-3731 (Never Use Alone) so someone can send help if you stop responding.

Open the interactive combination checker

Related combinations

• Mixing Opioids and Cocaine
• Mixing Benzodiazepines and Cocaine
• Mixing Alcohol and Cocaine
• Mixing Cocaine and Amphetamines
• Mixing Cocaine and MDMA
• Mixing Cocaine and Cannabis
• Mixing Cocaine and Ketamine
• Mixing Cocaine and GHB / GBL

This is educational information, not medical advice. "Low risk" never means "safe", and the potency of an unregulated supply is unknown.