Mixing Cocaine and MAOIs

Mixing Cocaine and MAOIs is dangerous and should be avoided — TripSit rates this combination “Dangerous.” Low risk never means safe.

This combination is poorly explored

Cocaine (also known as coke, crack) and MAOIs (also known as some antidepressants, syrian rue).

What to do

• Avoid this combination — the safest choice is not to mix them.
• Start with much less than usual and go slow — you can always take more, never less.
• Never use alone. If you do, call 1-800-484-3731 (Never Use Alone) so someone can send help if you stop responding.

Open the interactive combination checker

Related combinations

• Mixing Opioids and Cocaine
• Mixing Benzodiazepines and Cocaine
• Mixing Alcohol and Cocaine
• Mixing Cocaine and Amphetamines
• Mixing Cocaine and MDMA
• Mixing Cocaine and Cannabis
• Mixing Cocaine and Ketamine
• Mixing Cocaine and GHB / GBL

This is educational information, not medical advice. "Low risk" never means "safe", and the potency of an unregulated supply is unknown.