Mixing GHB / GBL and Pregabalin

Mixing GHB / GBL and Pregabalin is dangerous and should be avoided — TripSit rates this combination “Dangerous.” Low risk never means safe.

The two substances potentiate each other strongly and unpredictably, and may rapidly lead to unconsciousness. They both increase each other's side effects such as ataxia, sedation, and CNS depression. Blackout and memory loss risk is significantly increased. If the user falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position. There is an increased risk of seizures from this combination.

GHB / GBL (also known as G) and Pregabalin (also known as Lyrica).

What to do

• Avoid this combination — the safest choice is not to mix them.
• Keep naloxone (Narcan) within reach. It reverses opioid overdose and is safe to give if you are unsure.
• Start with much less than usual and go slow — you can always take more, never less.
• Never use alone. If you do, call 1-800-484-3731 (Never Use Alone) so someone can send help if you stop responding.

Open the interactive combination checker

Related combinations

• Mixing Opioids and GHB / GBL
• Mixing Benzodiazepines and GHB / GBL
• Mixing Alcohol and GHB / GBL
• Mixing Cocaine and GHB / GBL
• Mixing Amphetamines and GHB / GBL
• Mixing MDMA and GHB / GBL
• Mixing Cannabis and GHB / GBL
• Mixing Ketamine and GHB / GBL

This is educational information, not medical advice. "Low risk" never means "safe", and the potency of an unregulated supply is unknown.