Mixing Benzodiazepines and Ketamine

Mixing Benzodiazepines and Ketamine calls for caution — TripSit rates this combination “Caution.” Low risk never means safe.

Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position.

Benzodiazepines (also known as Xanax, Valium, Klonopin, Ativan) and Ketamine (also known as K, special K).

What to do

• Even for lower-risk pairs, the safest choice is not to mix — and never to use alone.
• Start with much less than usual and go slow — you can always take more, never less.
• Never use alone. If you do, call 1-800-484-3731 (Never Use Alone) so someone can send help if you stop responding.

Open the interactive combination checker

Related combinations

• Mixing Opioids and Benzodiazepines
• Mixing Benzodiazepines and Alcohol
• Mixing Benzodiazepines and Cocaine
• Mixing Benzodiazepines and Amphetamines
• Mixing Benzodiazepines and MDMA
• Mixing Benzodiazepines and Cannabis
• Mixing Benzodiazepines and GHB / GBL
• Mixing Benzodiazepines and Tramadol

This is educational information, not medical advice. "Low risk" never means "safe", and the potency of an unregulated supply is unknown.