Mixing Benzodiazepines and Tramadol

Mixing Benzodiazepines and Tramadol is dangerous and should be avoided — TripSit rates this combination “Dangerous.” Low risk never means safe.

Central nervous system- and/or respiratory-depressant effects may be additively or synergistically present. Vomit aspiration is a risk when passed out, lay down in recovery position if ingested.

Benzodiazepines (also known as Xanax, Valium, Klonopin, Ativan) and Tramadol.

What to do

• Avoid this combination — the safest choice is not to mix them.
• Keep naloxone (Narcan) within reach. It reverses opioid overdose and is safe to give if you are unsure.
• Start with much less than usual and go slow — you can always take more, never less.
• Never use alone. If you do, call 1-800-484-3731 (Never Use Alone) so someone can send help if you stop responding.

Open the interactive combination checker

Related combinations

• Mixing Opioids and Benzodiazepines
• Mixing Benzodiazepines and Alcohol
• Mixing Benzodiazepines and Cocaine
• Mixing Benzodiazepines and Amphetamines
• Mixing Benzodiazepines and MDMA
• Mixing Benzodiazepines and Cannabis
• Mixing Benzodiazepines and Ketamine
• Mixing Benzodiazepines and GHB / GBL

This is educational information, not medical advice. "Low risk" never means "safe", and the potency of an unregulated supply is unknown.