Mixing Benzodiazepines and MXE

Mixing Benzodiazepines and MXE calls for caution — TripSit rates this combination “Caution.” Low risk never means safe.

Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. Place the affected individual in the recovery position to prevent vomit aspiration from excess.

Benzodiazepines (also known as Xanax, Valium, Klonopin, Ativan) and MXE.

What to do

• Even for lower-risk pairs, the safest choice is not to mix — and never to use alone.
• Start with much less than usual and go slow — you can always take more, never less.
• Never use alone. If you do, call 1-800-484-3731 (Never Use Alone) so someone can send help if you stop responding.

Open the interactive combination checker

Related combinations

• Mixing Opioids and Benzodiazepines
• Mixing Benzodiazepines and Alcohol
• Mixing Benzodiazepines and Cocaine
• Mixing Benzodiazepines and Amphetamines
• Mixing Benzodiazepines and MDMA
• Mixing Benzodiazepines and Cannabis
• Mixing Benzodiazepines and Ketamine
• Mixing Benzodiazepines and GHB / GBL

This is educational information, not medical advice. "Low risk" never means "safe", and the potency of an unregulated supply is unknown.