Mixing Ketamine and Pregabalin

Mixing Ketamine and Pregabalin calls for caution — TripSit rates this combination “Caution.” Low risk never means safe.

Pregabalin and ketamine may synergize and increase each other's negative side effects such as nausea, dizziness, and loss of consciousness. Caution is advised for beyond medical dosages due to seizure concerns, and medical dosages for individuals with higher risk seizure profiles and or behavior.

Ketamine (also known as K, special K) and Pregabalin (also known as Lyrica).

What to do

• Even for lower-risk pairs, the safest choice is not to mix — and never to use alone.
• Start with much less than usual and go slow — you can always take more, never less.
• Never use alone. If you do, call 1-800-484-3731 (Never Use Alone) so someone can send help if you stop responding.

Open the interactive combination checker

Related combinations

• Mixing Opioids and Ketamine
• Mixing Benzodiazepines and Ketamine
• Mixing Alcohol and Ketamine
• Mixing Cocaine and Ketamine
• Mixing Amphetamines and Ketamine
• Mixing MDMA and Ketamine
• Mixing Cannabis and Ketamine
• Mixing Ketamine and GHB / GBL

This is educational information, not medical advice. "Low risk" never means "safe", and the potency of an unregulated supply is unknown.