Mixing MDMA and Mephedrone

Mixing MDMA and Mephedrone is dangerous and should be avoided — TripSit rates this combination “Dangerous.” Low risk never means safe.

Risk of serotonin syndrome as both drugs raise serotonin levels. Stimulants also increase the neurotoxic effects of MDMA, in addition to concerns of high blood pressure and unnecessary strain on the heart. As well as potentially causing anxiety and greater physical discomfort due to the combination.

MDMA (also known as ecstasy, molly) and Mephedrone (also known as 4-MMC, meow meow).

What to do

• Avoid this combination — the safest choice is not to mix them.
• Start with much less than usual and go slow — you can always take more, never less.
• Never use alone. If you do, call 1-800-484-3731 (Never Use Alone) so someone can send help if you stop responding.

Open the interactive combination checker

Related combinations

• Mixing Opioids and MDMA
• Mixing Benzodiazepines and MDMA
• Mixing Alcohol and MDMA
• Mixing Cocaine and MDMA
• Mixing Amphetamines and MDMA
• Mixing MDMA and Cannabis
• Mixing MDMA and Ketamine
• Mixing MDMA and GHB / GBL

This is educational information, not medical advice. "Low risk" never means "safe", and the potency of an unregulated supply is unknown.