Mixing MXE and MAOIs

Mixing MXE and MAOIs is unsafe and best avoided — TripSit rates this combination “Unsafe.” Low risk never means safe.

MAO-B inhibitors appear to increase the potency of MXE. MAO-A inhbitors have some negative reports associated with the combination but there isn't much information available

MXE and MAOIs (also known as some antidepressants, syrian rue).

What to do

• Avoid this combination — the safest choice is not to mix them.
• Start with much less than usual and go slow — you can always take more, never less.
• Never use alone. If you do, call 1-800-484-3731 (Never Use Alone) so someone can send help if you stop responding.

Open the interactive combination checker

Related combinations

• Mixing Opioids and MXE
• Mixing Benzodiazepines and MXE
• Mixing Alcohol and MXE
• Mixing Cocaine and MXE
• Mixing Amphetamines and MXE
• Mixing MDMA and MXE
• Mixing Cannabis and MXE
• Mixing Ketamine and MXE

This is educational information, not medical advice. "Low risk" never means "safe", and the potency of an unregulated supply is unknown.