Mixing Tramadol and Mescaline
Mixing Tramadol and Mescaline is unsafe and best avoided — TripSit rates this combination “Unsafe.” Low risk never means safe.
This combination can cause seizures due to the lowering of the threshold by tramadol and the potential of mescaline to cause seziures.
Tramadol and Mescaline (also known as peyote, San Pedro).
What to do
- Avoid this combination — the safest choice is not to mix them.
- Keep naloxone (Narcan) within reach. It reverses opioid overdose and is safe to give if you are unsure.
- Start with much less than usual and go slow — you can always take more, never less.
- Never use alone. If you do, call 1-800-484-3731 (Never Use Alone) so someone can send help if you stop responding.
Open the interactive combination checker
Related combinations
- Mixing Opioids and Tramadol
- Mixing Benzodiazepines and Tramadol
- Mixing Alcohol and Tramadol
- Mixing Cocaine and Tramadol
- Mixing Amphetamines and Tramadol
- Mixing MDMA and Tramadol
- Mixing Cannabis and Tramadol
- Mixing Ketamine and Tramadol
This is educational information, not medical advice. "Low risk" never means "safe", and the potency of an unregulated supply is unknown.