Mixing DXM and MXE

Mixing DXM and MXE is unsafe and best avoided — TripSit rates this combination “Unsafe.” Low risk never means safe.

There is a risk of serotonin syndrome when combining DXM with MXE, due to DXM and MXE both being SRI’s. MXE and DXM having notable affinities for the serotonin transporter.

DXM (also known as cough syrup, Robo) and MXE.

What to do

• Avoid this combination — the safest choice is not to mix them.
• Start with much less than usual and go slow — you can always take more, never less.
• Never use alone. If you do, call 1-800-484-3731 (Never Use Alone) so someone can send help if you stop responding.

Open the interactive combination checker

Related combinations

• Mixing Opioids and DXM
• Mixing Benzodiazepines and DXM
• Mixing Alcohol and DXM
• Mixing Cocaine and DXM
• Mixing Amphetamines and DXM
• Mixing MDMA and DXM
• Mixing Cannabis and DXM
• Mixing Ketamine and DXM

This is educational information, not medical advice. "Low risk" never means "safe", and the potency of an unregulated supply is unknown.