Mixing DXM and SSRIs
Mixing DXM and SSRIs is dangerous and should be avoided — TripSit rates this combination “Dangerous.” Low risk never means safe.
High risk of serotonin syndrome.
DXM (also known as cough syrup, Robo) and SSRIs (also known as most antidepressants).
What to do
- Avoid this combination — the safest choice is not to mix them.
- Start with much less than usual and go slow — you can always take more, never less.
- Never use alone. If you do, call 1-800-484-3731 (Never Use Alone) so someone can send help if you stop responding.
Open the interactive combination checker
Related combinations
- Mixing Opioids and DXM
- Mixing Benzodiazepines and DXM
- Mixing Alcohol and DXM
- Mixing Cocaine and DXM
- Mixing Amphetamines and DXM
- Mixing MDMA and DXM
- Mixing Cannabis and DXM
- Mixing Ketamine and DXM
This is educational information, not medical advice. "Low risk" never means "safe", and the potency of an unregulated supply is unknown.