Mixing DPH and LSD

Mixing DPH and LSD calls for caution — TripSit rates this combination “Caution.” Low risk never means safe.

At 25-50mg, DPH may assist with side effects of the LSD such as nausea and anxiety. At higher dosages, the combination of a deliriant (DPH) and LSD is cautioned against. LSD is likely to increase the deliriant and negative effects of DPH, in addition to increasing the risk of severe injury and mental trauma. LSD and DPH at recreational dosages have additional cardiac concerns such as vasoconstriction, tachycardia, hypertension, which in combination may be exacerbated.

DPH (also known as Benadryl) and LSD (also known as acid).

What to do

• Even for lower-risk pairs, the safest choice is not to mix — and never to use alone.
• Start with much less than usual and go slow — you can always take more, never less.
• Never use alone. If you do, call 1-800-484-3731 (Never Use Alone) so someone can send help if you stop responding.

Open the interactive combination checker

Related combinations

• Mixing Opioids and DPH
• Mixing Benzodiazepines and DPH
• Mixing Alcohol and DPH
• Mixing Cocaine and DPH
• Mixing Amphetamines and DPH
• Mixing Ketamine and DPH
• Mixing GHB / GBL and DPH
• Mixing Tramadol and DPH

This is educational information, not medical advice. "Low risk" never means "safe", and the potency of an unregulated supply is unknown.