Mixing MAOIs and SSRIs
Mixing MAOIs and SSRIs is dangerous and should be avoided — TripSit rates this combination “Dangerous.” Low risk never means safe.
MAOIs (also known as some antidepressants, syrian rue) and SSRIs (also known as most antidepressants).
What to do
- Avoid this combination — the safest choice is not to mix them.
- Start with much less than usual and go slow — you can always take more, never less.
- Never use alone. If you do, call 1-800-484-3731 (Never Use Alone) so someone can send help if you stop responding.
Open the interactive combination checker
Related combinations
- Mixing Opioids and MAOIs
- Mixing Benzodiazepines and MAOIs
- Mixing Alcohol and MAOIs
- Mixing Cocaine and MAOIs
- Mixing Amphetamines and MAOIs
- Mixing MDMA and MAOIs
- Mixing Cannabis and MAOIs
- Mixing Ketamine and MAOIs
This is educational information, not medical advice. "Low risk" never means "safe", and the potency of an unregulated supply is unknown.